The Best Small CRO for Biostatistics and FDA Submissions — Proven Since 1986

36+ Years. 500+ Clients. 750+ Successful Projects.

In high-stakes regulatory submissions, size isn’t what wins approvals — specialized expertise does.

Large CROs excel at scale, but when your project demands complex biostatistical analysis and strategic FDA navigation, a focused partner delivers better outcomes.

Since 1986, BSC® has been the leading small CRO for biostatistics and FDA submissions, helping clients turn complex clinical data into successful approvals.

Why BSC® Outperforms Larger CROs

Location: Philadelphia, United States + Remote

Focus: Biostatistics • Regulatory Strategy Consulting • Clinical Data Analysis CRO

Track Record: 36+ years in business, 500+ clients, 750+ projects completed

We specialize in the statistics and regulatory strategy that make or break an FDA submission.

Our work spans breakthrough medical devices, life-saving therapeutics, and diagnostics that have changed patient care.

  • Proven Success: Since 1986, we’ve guided 750+ projects through the FDA process.

  • Trusted by Industry Leaders: From early-stage medtechs to global giants whose internal folks need additional support.

  • High-Complexity Expertise: Adaptive designs, Propensity Score Matching, Bayesian methods, Endpoint creation, and real-world evidence that stands up to FDA scrutiny.

Specialized Expertise for Complex FDA Challenges

All of our statisticians and programmers do the work themselves — you’ll never be sold by one person during the business development call, and transferred to another after a contract is signed.

Our Services Include:

  • Clinical trial design that withstands FDA scrutiny

  • Statistical analysis plans aligned with your regulatory strategy

  • Data management and programming that pass audits

  • Complete biostatistics CRO regulatory submission packages (510(k), PMA, NDA)

Key Advantage: We know what FDA reviewers need to see — and how to present it.

When to Choose a Small CRO

Large CROs

Best for: Large-scale, global trials with high-volume patient recruitment.

Small CROs like BSC®

Best for: Complex biostatistical problems, adaptive trial designs, and strategic regulatory submissions.

If your submission requires specialized statistical expertise and tight regulatory alignment, a small CRO will often outperform a large generalist.

How to Evaluate a Biostatistics CRO

When choosing a partner for your FDA submission, look for:

  • Regulatory Track Record: Demonstrated approvals in your therapeutic area

  • Statistical Depth: Direct experience with your analytical challenges

  • Quality Systems: SOPs and compliance that withstand inspection

  • Technology Infrastructure: Current data management and analytics platforms

  • Senior Team Access: Direct communication with decision-makers

  • Proven References: Verified success with similar FDA projects

Why BSC® Is the Right Choice

We combine deep regulatory knowledge, advanced statistical methods, and direct senior-level engagement to get your submission approved.

Every month of delay in FDA clearance can cost millions in lost market opportunity.

Don’t risk it with a generalist CRO.

Let’s Get Your FDA Submission Approved

If your project demands sophisticated statistical analysis and proven regulatory strategy consulting, we should talk.

Email: hello@biomedstat.com

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The Strategic Edge in FDA Submissions: Applying "Least Burdensome"