Founder

Principal Biostatistician

Greg Maislin founded Biomedical Statistical Consulting in 1986 upon completing his graduate work at the Wharton School of the University of Pennsylvania. He has decades of experience applying statistical methods in medical device trials and in representing sponsors of medical device trials in FDA proceedings, including pre-submission and panel meetings.

As Adjunct Professor of Statistics in Medicine at the University of Pennsylvania Perelman School of Medicine, he serves as Director of the Biostatistics and Data Management Core for the Division of Sleep Medicine. He is an internationally recognized expert in biostatistical analysis in sleep research.

His statistical interests include methods for randomized clinical trials, propensity score methods to reduce bias in non-randomized studies, adaptive clinical trial designs including Bayesian statistical methods, longitudinal data analysis, and methods for missing data. He has authored or co-authored more than 200 scholarly articles in a wide range of medical research areas. His published work has been cited more than 25,000 times.

Greg holds a B.S. in Economics, an M.S. in Operations Research, an M.A. in Statistics, and completed coursework for a Ph.D. in statistics from The Wharton School of the University of Pennsylvania before founding BSC.

Greg has been married to Lu for more than 30 years. They have two sons, David and Brian. David works with his father at BSC.

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President and CEO

David Maislin takes pride in providing BSC's clients with the highest quality biostatistical support services. David joined BSC in 2012 and now serves as President and CEO. In his role as a Biostatistician, David works directly with clients and regulatory advisors throughout the lifecycle of FDA and Regulatory submissions. As President and CEO, David leads the day-to-day company operations of the BSC Team. He plays a key role in identifying, maintaining, and managing strategic partnerships and is responsible for ensuring the efficient execution of Company initiatives.

David specializes in developing innovative clinical trial designs that accommodate unique situations and data sets, including novel algorithms and simulations for Bayesian adaptive designs, longitudinal data analysis, complex CT and MRI data, missing data, and survival data. He has expertise in Probabilistic programming languages and extensive experience with R, SAS, IML, and SQL programming, as well as high-performance cloud computing.

Since 2016, David has also worked as a biostatistician for the University of Pennsylvania Perelman School of Medicine’s Center for Sleep and Circadian Neurobiology. He performs and presents the results from statistical analyses of NIH-funded clinical trials and develops algorithms to synchronize high-frequency cardiovascular data to support personalized medicine and telemedicine ventures.

David has co-authored studies on orthopedic devices and sleep apnea in journals including Quantitative Imaging in Medicine and Surgery, Journal of Spine & Neurosurgery, and Sleep. David studied at the Pennsylvania State University.

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Associate Principal Biostatistician

Brendan Keenan joined BSC in 2012. He designs clinical trials and statistical analysis plans; conducts simulated analyses of clinical trial characteristics; and performs advanced statistical programming techniques to report on the results of clinical trials. His primary focus is designing and implementing propensity score (PS) methods in clinical trials. He has played a key role in many FDA and other regulatory submissions, including as a blinded PS design statistician in multiple reviewed and approved spine and orthopedic PMA and 510k trials.

Brendan is also the co-director of the Biostatistics Core in the Division of Sleep Medicine at the University of Pennsylvania, where he oversees the day-to-day implementation of the strategy and activities of the Core. He collaborates with students and faculty in designing and implementing grant proposals and ongoing research projects within the Division. Previously, Brendan was the Biostatistician in the Center for Sleep and Circadian Neurobiology and Division of Sleep Medicine.

Brendan has a diverse background in academic research and varied statistical applications for several different diseases, including rheumatoid arthritis, systemic lupus erythematosus, Alzheimer’s disease, multiple sclerosis, and a variety of sleep and circadian disorders. He has co-authored at least 90 articles, including more than 100 related to sleep and sleep disorders.

Brendan earned a B.A. in Mathematics and Philosophy from Boston College and an M.S. in Biostatistics from the Harvard School of Public Health. He grew up in Boston and lives in New Jersey with his wife and sons.

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